Liver transplantation
Conditions
Interventions
Machine perfusion:Livers perserved using machine perfusion, with modified organ procurement and implantation technique
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
14 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Donor aged 14-60 years old, recipient aged 14-80 years old; (2) The donors are brain death donors; (3) Primary liver transplant reipients; (4) The recipient and family agree to receive livers preserved using machine perfusion
Exclusion criteria
Exclusion criteria: (1) Combined organ transplantation or multivisceral transplantation; (2) ABO-hblood type mismatch; (3) Vessel variants leading to inability to NMP perfuse the livers; (4) Without willingness or ability to comply with the study procedure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak AST level in the first 7 days post-transplantation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peak ALT, Tbil, INR levels within the first week post-transplantation;Early allograft dysfunction;Primary non-function;ischemic-type biliary lesion;graft survival;patient survival;histology of liver grafts; | — |
Countries
China
Contacts
Public ContactXiaoshun He
The First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed