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The relationship between mutation frequency of EGFR 19-Del in cfDNA and the effects of TKI treatment on first-line

The relationship between mutation frequency of EGFR 19-Del in cfDNA and the effects of TKI treatment on first-line

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OPN-17010613
Enrollment
Unknown
Registered
2017-02-12
Start date
2017-07-04
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung carcinoma

Interventions

Treated:none

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) aged more than 18 years; 2) the pathological diagnosis of non-small cell lung cancer; 3) the Eastern Cooperative Oncology Group performance status score of 0-1; 4) neutrophil than 1500/L, more than 100000/ of platelet L; 5) according to the seventh edition of AJCC staging of tumor stage IV; 6) first visit the sick man.

Exclusion criteria

Exclusion criteria: 1) previous medical history of the patients; 2) severe infection control;3) albumin level less than 30g/l; 4) pregnancy, while suffering from other malignant tumors, may affect drug absorption of digestive system diseases; 5) patients refused entry into the group; 6) maintenance treatment patients.

Design outcomes

Primary

MeasureTime frame
mutation amplititude;

Countries

China

Contacts

Public ContactZhenyu Ding

Oncology Department, West China Hospital, Sichuan University

dingzy333@163.com+86 18980601957

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026