Type 2 diabetes
Conditions
Interventions
insulin group:insulin treatment
metformin group:metformin treatment
acarbose group:acarbose treatment
Sponsors
Nanjing First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Newly-diagnosed patients with T2DM; 2. Aged from 18 to 80 years old; 3. Voluntary and signed informed consent; 4. Able to do exercise and control diet; 5. HbA1c 6.5-13.5%.
Exclusion criteria
Exclusion criteria: 1. Patients with alanine aminotransferase (ALT) levels more than 2.5 times the upper normal range or Cr levels more than 1.3 the upper normal range; 2. Patients with a history of systemic corticosteroids use in 3 months; 3. Noncompliance in exercise or diet control; 4. Patients with infection in 4 weeks; 5. pregnant; 6. Patients with acute metabolic diabetic complications such as ketoacidosis or hyperosmolar state (coma); 7. Any other condition that is improper for this study judged by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treg;TH1 cell;TH2 cell;TH17 cell;LP-PLA2; | — |
Secondary
| Measure | Time frame |
|---|---|
| glycated serum protein;Fast blood glucose; | — |
Countries
China
Contacts
Public ContactJian-hua Ma
Nanjing First Hospital
Outcome results
None listed