severe ocular trauma
Conditions
Interventions
2:Within 48 hours of an emergency debridement while intervention vitrectomy
Control:Intervention vitrectomy will be conducted after emergency debridement two weeks
Sponsors
Southwest Hospital, Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. patients aged 18-75 years (including 18 years of age and 75 years of age) willing to sign an informed consent form; 2. patients within 48 hours after the injury admissions while at least one eye (unilateral) or both eyes due to eye trauma and meet one of the following criteria: 1) rupture (Zone III injuries involving the retina causing retinal incarceration or detachment); 2) penetrating trauma (injuries involving the retina causing retinal incarceration or III District detachment, penetrating injuries); 3) endophthalmitis tendency; 4) Exclude routine emergency vitrectomy (high purity copper and iron, inner organic intraocular foreign body) of other foreign body retinal traction, traumatic detachment; 3. heart and lung liver and kidney function was normal; 4. decreased vision due to eye trauma rather than for other reasons; 5. voluntarily choose vitrectomy patients; 6. can be observed with the adverse events and efficacy; 7. No other eye diseases; 8. normal blood coagulation; 9. female patient was negative pregnancy test; 10. good compliance, to comply with the study or follow-up process.
Exclusion criteria
Exclusion criteria: 1. With the eye / Disease: (1) Study on the Eye hinder research to improve the treatment of diseases associated with vision; (2) the study eye that could affect the interpretation of the results or may result in damage to eyesight or require medical or surgical intervention in the six-month period of treatment of other diseases; (3) the presence of post-impact study eye intraocular pressure control of the entire circumference of the ciliary body detachment; 2. The general condition or treatment; (1) or abnormal clotting function currently being used anticoagulant drugs (such as aspirin) treatment; (2) stroke, coronary heart disease, history of angina and renal dysfunction require dialysis or kidney transplantation, and other unsuitable in a clinical trial of systemic chronic diseases; (3) current or recent use may require general known to the lens, the retina or optic nerve toxic drugs, including chloroquine / hydroxychloroquine, phenothiazines, ethambutol, deferoxamine and tamoxifen, etc.; 3. Compliance (1) can not be observed with the adverse events and efficacy; (2) research or follow-up process can not comply.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eye preservation rate;Reattachment rate;vision; | — |
Secondary
| Measure | Time frame |
|---|---|
| intraocular pressure; | — |
Countries
China
Contacts
Public ContactLiu Yong
Southwest Hospital of Third Military Medical Universit
Outcome results
None listed