Stage I Non-small Cell lungCcancer
Conditions
Interventions
Experimental group:Stereotactic Body Radiotherapy
The control group:Surgery
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients were required to be >=18 years old, with an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2 and weight loss 50% predicted; 6. Willing and able to comply the protocol and attend all study visits, provide written informed consent prior to the initiation of any study-related procedures; 7. WOCBP using and willing to continue to use adequate contraceptive precautions for the duration of the study.
Exclusion criteria
Exclusion criteria: 1. Patients with any component of small cell lung carcinoma; 2. Patients with evidence of a malignant pleural or pericardial effusion or patients with T4 disease with radiographic evidence of massage invasion of a large pulmonary artery and tumor causing significant narrowing and destruction of that artery; 3. Who received previous thoracic radiotherapy, previous surgery, previous chemotherapy with bleomycin, regular use of supplemental oxygen; 4. Pregnancy or lactation or who plan to pregnant; 5. Who have oher malignancies (with the expection of cases of cervical carcinoma in situ or non-malignant melanoma skin cancer that had been clinically cured for at least 5 years); 6. Severe, active co-morbidity, such as human immunodeficiency virus,acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration, hepatic insufficiency resulting in clinical jaundice and/or coagulation defects, chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of registration, poorly controlled diabetes; 7. Patients who are participating in a concurrent treatment protocol; 8. The subject may not the study because of other study, or researchers think are unsuitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival rate;Progress control of local rate; | — |
Countries
China
Contacts
Public ContactHeJian
Outcome results
None listed