hypertension and hyperlipidemia
Conditions
Interventions
1:amlodipine/atorvastatin 5mg/10mg
Sponsors
Peking university third hospital cadiology department
Eligibility
Sex/Gender
All
Age
34 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. age 30-65 year-old male or female; 2. blood pressure between 140/90mmHg and180/110mmHg; 3. new diagnosed hypertension or hypertension history but do not have any antihypertesive drugs for the past 2 weeks; 4. hyperlipidemia history or rencent hyperlipidemia (LDL-C more than 3.37mmol/or T-CHO more than 5.18mmol/L); 5. agree to Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. secondary hypertension; 2. left ventricular dysfunction (LVEF less than 50%) or accroding NYHA heart funtion are class III-IV; 3. Active liver disease or signifcant abnomal hepatic function (ALT more than 3.0*ULN and or bilirubin more than 1.5*ULN); 4. severe chronic renal disease,Measured or estimated eGFR less than 30ml/min/1.73m2 or renal dialysis; 5. diagnosed coronary heart disease; 6. diagnosed type 1 or type 2 diabetes; 7. hemorrhagic or ischemic cerebral vascular disease; 8. pregnant or lactating women; 9. infectious diseases in the past three months; 10. tumor history; 11. autoimmune diseases; 12. various causes of bleeding disorders; 13. taking aspirin in 2 weeks; 14. with life expectancy shorter than 12 months of clinical concomitant diseases, or can not complete all follow-up; 15. known allergic to amlodipine or HMG-CoA reductase inhibitors, or had a serious adverse reaction due to taking these drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| microparticles; | — |
Countries
China
Contacts
Public ContactZu lingyun
Outcome results
None listed