COPD
Conditions
Interventions
Bacillus group:Drugs
Cocci group:Drugs
Spiral bacteria group:Drugs
Sponsors
The Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. aged 40-79 years male and female; 2. with cough, sputum or dyspnea and other symptoms, chest imaging with emphysema performance, lung function criteria include: inhalation of bronchodilator FEV1 / FVC ratio = 70%; 3. without respiratory infection and acute exacerbation of COPD in past four weeks; 4. 30 days before screening, no antibiotics were used; 5. GOLD assessed as B or C patients.
Exclusion criteria
Exclusion criteria: 1. patients with COPD in addition to other respiratory diseases, such as asthma, asthma, interstitial pneumonia, active tuberculosis, community-acquired pneumonia, lung cancer, bronchiectasis, pulmonary heart disease, pulmonary embolism; 2. patients with grade C need to be combined with ICS 3. 30 days before screening, patients used antibiotics; 4. Patients with alcohol or narcotic drug abuse, drug history, or psychiatric history (such as schizophrenia, obsessive-compulsive disorder, depression), confrontation, negative motives, suspicion or other emotional or intellectual problems may affect participation in this study Effectiveness of the situation; 5. is participating in other drug clinical trial project, or stop time is less than 3 months; 6. patients induced sputum culture as a fungus or virus infection or its airway micro-ecological detection does not meet the bacilli, cocci or spiral group of patients; 7. patients can not cooperate with the relevant inspection of the project, do not agree to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung function; | — |
Secondary
| Measure | Time frame |
|---|---|
| The frequency of acute exacerbations of the past year; | — |
Countries
China
Contacts
Public ContactBin Wu
The Affiliated Hospital of Guangdong Medical University
Outcome results
None listed