Thoracic surgery
Conditions
Interventions
Case series:opioid analgesia after thoracic surgery
Sponsors
Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,
Eligibility
Sex/Gender
All
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: 1. ASA classification I~ II; 2. Aged 18~69 years old; 3. The purpose and risk of this study was fully understood before the operation, and informed consent was signed;
Exclusion criteria
Exclusion criteria: 1. Patients with a history of opioid addiction; 2. Patients with severe cardiovascular disease; 3. Patients with liver and renal insufficiency; 4. Take a monoamine oxidase inhibitor(MAOI)or disuse within two weeks; 5. Pregnancy; 6. Chronic pain history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain related genes polymorphism;Description of the general epidemiology of CPTP;The correlation between pain related genes polymorphism and CPTP;The correlaction between CYP enzyme gene polymorphism and the analgesia effect as well as demand of oxycodone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain threshold;VAS; | — |
Countries
China
Contacts
Public ContactXianwei Zhang
Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed