Cancer Cachexia
Conditions
Interventions
Intervention group:Matrine injection or Kanglaite injection
Control group:Methylphenidate tablets
Sponsors
Shanghai Jiaotong University Affiliated Sixth People 's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Diagnosis: 1. clear colon cancer, lung cancer, gastric cancer and pancreatic cancer histopathological diagnosis; 2. 6 months weight loss ? 5%; or body mass index 2%. Inclusion criteria: 1. in line with the diagnosis and treatment of malignant tumor in the middle and late stage; 2. expected survival time longer than 6 months; 3. aged 18 to 80 years old; 4. ECOG score ? 3 points; 5. meet the Qi-Xue deficiency of traditional Chinese medicine syndrome: diet reduced, pale yellow, knee weakness, mental fatigue, long illness wasting. 6volunystary treatment, informed consent and good compliance
Exclusion criteria
Exclusion criteria: 1. pregnant women; 2. gastrointestinal obstruction; 3. thrombosis history; 4. diabetes, hypertension, mental illness, severe cardiovascular and cerebrovascular disorders; 5. moderate and severe liver and kidney dysfunction; 6. treatment wound cause weight and metabolic changes (such as high dose of hormones).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life Score;Body weight Change; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutrition status(PG-SGA score);KPS score;Pain score;Survival time;GPS Score;Chinese medicine syndrome score;ECOG Score;grip strength of non dominant hand;IL-6; | — |
Countries
China
Contacts
Public ContactGuo Cheng
Shanghai Jiaotong University Affiliated Sixth People 's Hospital
Outcome results
None listed