Gram Positive Bacteria Infection
Conditions
Interventions
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients have been diagnosed as gram-positive infections and treated by vancomycin In accordance with the following requirements: 1. Unlimited gender, age and weight; 2. Confirm the patients of gram-positive infections by clinical symptoms, signs, laboratory and pathogenic microorganism examination, such as bloodstream infection, pulmonary infection, abdominal cavity infection, central nervous system infection, skin and soft tissue infection, urinary tract infection; 3. Received vancomycin>5 days; Selected patients:Bloodstream infection, pulmonary infection (except coagulase negative staphylococcus), abdominal cavity infection, central nervous system infection,skin and soft tissue infection (except coagulase negative staphylococcus), urinary tract infection caused by Staphylococcus aureus, Enterococcus, Streptococcus; 4. Require the use of vancomycin; 5. Allergic patients to ß-lactam antibiotics such as penicillin and cephalosporin can also be selected; 6. Patients with informed consent.
Exclusion criteria
Exclusion criteria: 1. Any patient conforms to the following items is not the object of investigation; 2. Patients effectively treated by anti-gram-positive agents within 72 hours before being selected, such as norvancomycin,teicoplanin, linezolid, and fusidic acid, compound SMZ/TMP,tigecycline and daptomycin; 3. Patients with colonized gram positive cocci or not infected; 4. Vancomycin treatment within 5 days (Except hemodialysis and peritoneal dialysis patients); 5. Pregnancy or breastfeeding women; 6. Patients combined with aminoglycosides; 7. Patients lacking of clinical infection and laboratory evaluation index and could not be evaluated the clinical efficacy and safety; 8. Participat in other clinical trials within 1 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| effecacy and safety; | — |
Countries
China
Contacts
Public ContactJing Zhang, Jufang Wu
Huashan Hospital, Fudan University
Outcome results
None listed