Schizophrenia
Conditions
Interventions
male aripiprazole:aripiprazole
female aripiprazole:aripiprazole
male olanzapine:olanzapine
female olanzapine:olanzapine
Sponsors
Jiangxi Mental Health Centre
Eligibility
Sex/Gender
All
Age
18 Years to 48 Years
Inclusion criteria
Inclusion criteria: These people were experiencing their first psychotic episode of schizophrenia diagnosed in accordance with criteria established in DSM-V and had not previously received any antipsychotic drug treatment. The Positive and Negative Syndrome Scale (PANSS) total score = 60. Aged 18-65 years agreed to enroll in the trial and signed an informed consent.
Exclusion criteria
Exclusion criteria: Any other psychiatric disorder other than schizophrenia (according to DSM-V); history of any significant substance abuse met DSM-V criteria, including addiction to cocaine or alcohol; a significant risk of committing suicide based on history or mental status exam; pregnant or lactating patients; specific systemic diseases; or other medical conditions such as diabetes mellitus, dyslipidemia, cardiovascular diseases, and hypertension; clinically significant abnormal laboratory test results, vital sign, or electrocardiogram findings.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body mass index (BMI);Waist: hip ratio (WHR);Serum levels of fasting glucose;Serum lipids;Serum Leptin;Serum High Molecular Weight Adiponectin;Serum Ghrelin;Serum Insulin; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Positive and Negative Syndrome Scale (PANSS); | — |
Countries
China
Contacts
Public ContactXuemei Zhou
Jiangxi Mental Health Centre
Outcome results
None listed