defects of nasal mucosa
Conditions
Interventions
treatment group:Covering tissue regeneration membrane
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Male and female aged 18-70 years; 2. Not to participate in other clinical trails in three months before the start of the test ; 3. Indications: nasal sinus diseases (sinusitis and nasal polyps, benign tumor, nasal septum lesions, etc.) shall be line operation and cause the defects of nasal mucosa (wound maximum linear distance is greater than 1 cm); 4. After obtaining informed, voluntary and signed the informed consent. Note: for patients with bilateral, both sides are repaired, are evaluated.
Exclusion criteria
Exclusion criteria: 1. Severe liver and kidney dysfunction, metabolic syndrome, cardiovascular disease such as systemic disease cannot tolerate surgery; 2. During pregnancy or lactation women and patients with plan of pregnancy during the study period; 3. Allergy of collagen products; 4. The long-term use of immune inhibitor; 5. Can't tolerance of patients with general anesthesia; 6. With mental illness or mental abnormal; 7. Poor compliance, can't do with according to the visitor; 8 patients with surgical contraindication; 9. Other researchers determine does not comply with the conditions of patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete epithelial change rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mucosal morphology change;Mucous membrane outcome 3 phase percentage;Subjective evaluations; | — |
Countries
China
Contacts
Public ContactYongfang Wang
Yantai Zhenghai Bio-Tech Co., Ltd.
Outcome results
None listed