eyes with primary angle closure
Conditions
Interventions
One cohort:Investigating the IOP lowering effect and the safety profile iStent Supra implantation in Chinese eyes with PAC or PACG, twelve months
Sponsors
The Chinese University of Hong Kong
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. PAC or PACT Chinese patients who are 18 years of age or above; 2. The trabecular meshwork is not visible for more than 180 degree on dark room gonioscopy; 3. IOP >22mmHg; 4. Without secondary causes of angle closure identified. PACG is diagnosed in eyes with PAC with evidence of glaucomatous optic disc damage (i.e. narrowing of neuroretinal rim, thinning of retinal nerve fiber layer, optic disc excavation with or without corresponding visual field defects); 5. A clear view of the angle at the intended implantation site, via gonioscopy at the screening visit and again at the operative exam.
Exclusion criteria
Exclusion criteria: 1. Peripheral anterior synechiae more than 180 degree at the nasal side; 2. Visual acuity worse than 6/60, pseudophakic, phakic with cataractous lens expected to require cataract surgery within 12 months of the screening exam; 3. The presence of advanced visual field defects with mean deviation (MD) <-18 dB; 4. Chronic or recurrent uveitis; 5. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IOP reduction from preoperative IOP at 12 months of follow-up.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigate the side effect of iStent.; | — |
Countries
China
Contacts
Public ContactDr. Leung Kai Shun Christopher
The Chinese University of Hong Kong
Outcome results
None listed