Autism Spectrum Disorder
Conditions
Interventions
Group A:before treatment
Group B:bumetanide
Sponsors
Shanghai Children's Medical Center,Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients, aged from 3 to 12 years old, were given the diagnosis of ASD according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) , by a team of autism experts; Scores for Children Autism Rating Scale (CARS) were more than 30; Signed Informed Consents were provided by parents.
Exclusion criteria
Exclusion criteria: Liver and kidney dysfunction; With a history of allergy to sulfa drugs; abnormal ECG; chromosomal abnormality; suffering from nervous system diseases (such as epilepsy, schizophrenia, and so on); using the melatonin treatment for sleep disorders or withdrawal less than three weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADOS score;CARS score;ADI-R score;GESELL score;CGI score;imaging score; | — |
Countries
China
Contacts
Public ContactFei Li
Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine
Outcome results
None listed