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Effect of low dose aspirin on serum inflammatory factors of PCOS female and its correlation with their outcomes of IVF/ICSI cycles: a prospective cohort study

Effect of low dose aspirin on serum inflammatory factors of PCOS femal and its correlation with their outcomes of IVF/ICSI cycles: a prospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OPC-16008328
Enrollment
Unknown
Registered
2016-04-20
Start date
2016-04-27
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovary syndrome

Interventions

PCOS with HA:low dose aspirin
PCOS with NHA:low dose aspirin
PCOS with IR:low dose aspirin
PCOS with NIR:low dose aspirin
PCOS with Obesity:low dose aspirin
PCOS with NOB:low dose aspirin
PCOS with metabolic syndrome:low dose aspirin
PCOS without metabolic syndrome:low dose aspirin

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
21 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1)diagnosed as PCOS patients. (2)aged 21-40 years. (3)demanding IVF/ICSI treatment. (4)informed concent.

Exclusion criteria

Exclusion criteria: 1. Allergy to Aspirin and other NSAIDs; 2. History of Nasal polyps syndrome and asthma; 3. History of circulatory system diseases(e.g. moderate to severe iron-deficency anemia, hemophilia and thrombocytopenia); 4. ulceration of digestive system; 5. Hemorrhagic cerebrovascular disease; 6. hepatic renal dysfunction, cardiac insufficiency; 7. Other major diseases; 8. Usage of steroids, anticoagulation drugs, thrombolytic agent, antiacid or antidiabetic drugs.

Design outcomes

Primary

MeasureTime frame
CRP;TNF-a;IL-6;

Secondary

MeasureTime frame
IVF/ICSI outcome;

Countries

China

Contacts

Public ContactJie Qiao

Peking University Third Hospital

jie.qiao@163.com+86 010-82266752

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026