FindTrial
Sign In

Clinical research on the pathogenesis and differential diagnosis of diabetes mellitus secondary to chronic pancreatitis

Clinical research on the pathogenesis and differential diagnosis of diabetes mellitus secondary to chronic pancreatitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OPC-16008322
Enrollment
Unknown
Registered
2016-04-19
Start date
2016-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic pancreatitis associated pancreatic diabetes.

Interventions

Chronic pancreatitis associated type 3c diabetes mellitus:Consuming a 250ml standard mixed meal
Type 2 diabetes mellitus:Consuming a 250ml standard mixed meal
Healthy control:Consuming a 250ml standard mixed meal

Sponsors

ChangHai Hospital, Second Military Medical University, Shanghai, China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for chronic pancreatitis: CP was included on the bases of morphological and pathological diagnostic criteria. 2. Inclusion criteria for diabetes mellitus secondary to chronic pancreatitis: Diabetes mellitus secondary to chronic pancreatitis was included if exocrine pancreatic insufficiency (faecalelastase-1 levels <200 mg/g) and pathologic imaging results were present in the absence of diabetes-associated antibodies. 3. Inclusion criteria for type 2 diabetes mellitus: Type 2 diabetes mellitus in accordance with the criteria of the American Diabetes Association was included.

Exclusion criteria

Exclusion criteria: Exclusion criteria for chronic pancreatitis and chronic pancreatitis associated diabetes mellitus: 1. presence of type 1 or 2 diabetes mellitus or ketosis before onset of chronic pancreatitis; 2. any other concurrent pancreatic disease; 3. beyond the age range of 18 to 65 years old; 4. the pregnant; 5. unwilling to be recruited; Exclusion criteria for type 2 diabetes mellitus: 1. presence of type 1 diabetes mellitus associated autoimmune markers; 2. any other concurrent pancreatic disease; 3. beyond the age range of 18 to 65 years old; 4. the pregnant; 5. unwilling to be recruited.

Design outcomes

Primary

MeasureTime frame
Pancreatic polypeptide;Fasting insulin;Faecalelastase-1;Fasting glucose;Fasting C-peptide;HbA1c;—

Secondary

MeasureTime frame
Glucagon;Somatostatin;Glucagon-like peptide 1 (GLP-1);Incretin;—

Countries

China

Contacts

Public ContactXu Maojin

ChangHai Hospital, Second Military Medical University

xumaojinch@126.com+86 13601698168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026