advanced gastric cancer
Conditions
Interventions
Sponsors
Jiangsu Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18~75 years old, man or woman is allowed; 2. Pathologically histology and/or cytological diagnosis with advanced gastric cancer; 3. ECOG score 0-2; 4. The expected survival more than three months; 5. The main organ function, that meet the following criteria: (1) subject to the standard blood test (14 days not blood transfusion and blood products, not using G-CSF and other hematopoietic stimulating factor corrected): a.HB>=90 g/L; b.ANC>=1.5*10^9/L; c.PLT>=80*10^9/L; (2)biochemical tests must meet the following criteria: a.TBIL 45 ml/min (Cockcroft-Gault formula); 6. patients who physicians consider that treatment can bring benefit; 7. AFP positive:serum AFP >ULN+35µg/L(carry on pathological examination after patient's consent); 8. Patient has to voluntarily join the study and sign the Informed Consent Form for the study.
Exclusion criteria
Exclusion criteria: 1. patients who are allergic to lapatinib or any of the ingredients in lapatinib tablets; 2. Pregnant or lactating women; 3. patients with contraindication(active bleeding,ulcerative lesions, enterobrosis, ileus,major surgery within 30days,uncontrolled hypertension drugs, level III -IV cardiac insufficiency,severe liver and kidney function is not complete); 4. patients who physicians suggest not be included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS; | — |
Countries
China
Contacts
Public ContactChen Jia
Jiangsu Cancer Hospital
Outcome results
None listed