AIDS
Conditions
Interventions
A:HIV-RNA viral load test (quantitative), immunology, blood routine and hepatorenal function test (quantitative) will be performed 0, 3, 6 and 12 months after treatment initiation respectively. Nation
B:HIV-RNA viral load test (quantitative), immunology, blood routine, and liver and hepatorenal function test (quantitative) will be performed 0, 3, 6 and 12 months after treatment initiation respectiv
C:According to current national guideline, HIV-RNA viral load test (quantitative) will be perfomed once a year
immunology, blood routine and hepatorenal function test (quantitative) will be performed 2-4 times each year. National first-line regimen will be applied: AZT/TDF+3TC+EFV/NVP.
Sponsors
8th People's Hospital of Guangzhou
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Subjects: 250 HIV treatment-naive patients who are above 18 years old with CD4+>200 /uL will be enrolled and assigned to different groups.
Exclusion criteria
Exclusion criteria: not available
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients with HIV-1 RNA< 50 copies/ml in ITT population analysis at Week 48;HIV-1 RNA< 400 copies/ml in ITT population analysis at Week 24; safety, the proportion of patients without alteration of initial regimen and the drug resistance analysis results of treatment failure cases at Week 24 and Week 48; immunological response at Week 24 and Week 48.; | — |
Countries
China
Contacts
Public ContactWeiping Cai
Outcome results
None listed