Hypertension
Conditions
Interventions
Case series:felodipine 5mg
hydrochlorothiazide 25mg
Sponsors
Institute of Clinical Pharmacology, Central South University
Eligibility
Sex/Gender
Male
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Healthy men,aged between 19~40y,and the age years difference among the subjects is no more than 10y in one trial; 2. Weight over than 50kg, and in the scope of +/-10% ideal weight; 3. Without gastrointestinal tracts diseases, liver or severely kidney injury; 4. Without supersensitive history on drugs, and without postural hypotension; 5. Take no medicine drugs in last two weeks before trials; 6. All subjects sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. Systolic blood pressure 100/min; 2. With the supersensitive history on drugs, and supersensitive with telmisartan; 3. Participated other clinical trails in last three months, or taken any other drugs in last two weeks; 4. With gastrointestinal tracts diseases, liver or severely kidney injury.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood drug concentration; | — |
Countries
China
Contacts
Public ContactWei Zhang
Outcome results
None listed