The Influece of Gene Polymorphisms on The Consumpation of Sufentail in Neurosurgery

A study for influece of CYP3A4*1GPolymorphisms on The Consumpation of Sufentail in Neurosurgery

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OPC-15006206

Enrollment

Unknown

Registered

2015-03-13

Start date

2015-03-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurosurgery

Interventions

Case series:sufentanil

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: To be aged between 20 and 60 years who were scheduled for elective trigeminal nerve decompression or facial nerve decompression were enrolled.

Exclusion criteria

Exclusion criteria: 1. cardiovascular or respiratory complications; 2. disorder of endocrine system; 3. allergy to sufentanil; 4. liver and renal impairments; 5. the BMI (body mass index)>=28kg/m2; 6. current medication(s) including either the CYP3A4 inducers or/and inhibitors and 7. the ASA (American Society of Anesthesiologists) physical status more than II.

Design outcomes

Primary

Measure	Time frame
sufentail consumpation;	—

Secondary

Measure	Time frame
heart rate;blood pressure;	—

Countries

China

Contacts

Public ContactRongliang Xue

1071529137@qq.com+86 13991261135

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026