cervical cancer
Conditions
Interventions
trial group:Use Oncorine
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. It was diagnosed as cervical cancer according to histopathology. Locally advanced cervical cancer patients haven't radiotherapy and chemotherapy history; 2. Diameter of tumor on CT image was bigger than 6cm; 3. Age: 18 – 65 years old; 4. Karnofsky >=60; 5. Blood routine examination is normal. And coagulation and hemorrhage disorders are not serious; 6. Patients could understand aims of the trial and take part in it voluntarily and sign informed consent; 7. Important organs' function, such as heart, lung, liver, kidney, don't have serious disorder. And radiotherapy and chemotherapy could be tolerant.
Exclusion criteria
Exclusion criteria: 1. Other malignancies are presence at the same time. And it hasn't been cure; 2. Active infection patients in clinical; 3. Allergy history in biologics; 4. Women are in pregnant or in lactation; 5.Have serious internal diseases. Biotherapy, radiotherapy and chemotherapy could not be tolerant; 6. Antiviral drugs and targeted drugs are being using; 7. Large doses of glucocorticoids or other immunosuppressants are used in one month; 8. HIV-positive or other acquired, congenital immunodeficiency diseases. Has organ transplant history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| objective efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| objective response rate;PFS;OS; | — |
Countries
China
Contacts
Public ContactHua Yu
Outcome results
None listed