acute cerebral infarction
Conditions
Interventions
test group:Standardized treatment protocols of Ischemic stroke and urinary kallidinogenase Injection
Control:Standardized treatment protocols of Ischemic stroke
Sponsors
The First Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Consecutive patients with admitted to the hospitals with acute cerebral infarction within 48 hours of symptoms onset, and diagnosed as middle cerebral artery stenosis bycomputed tomographic angiography (CTA) examinations within 48h of hospital admission; 2. Age of 18-80 years old; 3. Patients with clear consciousness; 4. Patients or their legal representative has signed the "informed consent".
Exclusion criteria
Exclusion criteria: 1. Hemorrhagic stroke; 2. Transient ischemic attack (TIA); 3.Bleeding tendency caused by blood diseases, hemorrhage of digestive tract and so on; 4. With severe liver dysfunction or renal dysfunction; 5. Patients with atrial fibrillation or serious heart diseases; 6. Plan to major surgery, carotid endarterectomy or stenting angioplasty; 7. Patients with malignant tumor or intracranial tumor; 8. Pregnant women, pregnancy planners or lactation period women; 9. Patients who are known to have an allergy to Urinary kallidinogenase Injection; 10. Patients applied or are applied thrombolytic drug within two weeks; 11. Currently participating in the clinical research of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CTA-MIP collateral score;National Institutes of Health Stroke Scale (NIHSS);Barthel Index;Modified Rankin Scale;The incidence of endpoint events; | — |
Countries
China
Contacts
Public ContactFeng Hong-Lin
Outcome results
None listed