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Effect of acupuncture on the DMN of brain in patients with major depressive disorder: a resting-state fMRI study

Effect of acupuncture on the DMN of brain in patients with major depressive disorder: a resting-state fMRI study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OPC-15005873
Enrollment
Unknown
Registered
2015-01-23
Start date
2012-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depressive disorder

Interventions

depressive group, healthy subjects:acupuncture at Baihui lasting 20min

Sponsors

First Affiliated Hospital, Guangxi University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 50 Years

Inclusion criteria

Inclusion criteria: All the MDD patients were individually diagnosed by two trained psychiatrists using the structured clinical interview of the Diagnostic and Statistical Manual of Mental Disorders-fourth criteria (DSM-IV) [32] and met the following criteria: (1) first-episode, drug-na?ve; (2) between the ages of 18 and 60 years; (3) being right-handed; And (4) currently episode experience of MDD with the score of at least 18 on 17-items Hamilton Depression Rating Scale (HDRS-17).

Exclusion criteria

Exclusion criteria: (1) DSM-IV criteria for other diagnoses that included schizoaffective disorder, schizophrenia, organic mental disorders, delusional mental disorder, psychotic features coordinated or uncoordinated with mood or bipolar disorder; (2) history of head injury or neurological disorder and degenerative diseases such as movement disorders and Parkinson’s disease); (3) acutely suicidal or homicidal or requiring inpatient treatment; (4) any MRI contraindications; (5) all of acupuncture in patients with contraindications; (6) assessment of acupuncture needling non-responders. All subjects did not smoke, no lactating women.

Design outcomes

Primary

MeasureTime frame
activity in brain regions (ALFF, ReHo);Brain functional connectivity;

Countries

China

Contacts

Public ContactDemao Deng
demaodeng@163.com+86 13507880885

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026