depressive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All the MDD patients were individually diagnosed by two trained psychiatrists using the structured clinical interview of the Diagnostic and Statistical Manual of Mental Disorders-fourth criteria (DSM-IV) [32] and met the following criteria: (1) first-episode, drug-na?ve; (2) between the ages of 18 and 60 years; (3) being right-handed; And (4) currently episode experience of MDD with the score of at least 18 on 17-items Hamilton Depression Rating Scale (HDRS-17).
Exclusion criteria
Exclusion criteria: (1) DSM-IV criteria for other diagnoses that included schizoaffective disorder, schizophrenia, organic mental disorders, delusional mental disorder, psychotic features coordinated or uncoordinated with mood or bipolar disorder; (2) history of head injury or neurological disorder and degenerative diseases such as movement disorders and Parkinson’s disease); (3) acutely suicidal or homicidal or requiring inpatient treatment; (4) any MRI contraindications; (5) all of acupuncture in patients with contraindications; (6) assessment of acupuncture needling non-responders. All subjects did not smoke, no lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| activity in brain regions (ALFF, ReHo);Brain functional connectivity; | — |
Countries
China