Effect of miRNA21 evaluating the progression of acute kidney injury following open heart surgery

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OPC-14005728

Enrollment

Unknown

Registered

2014-12-22

Start date

2015-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury following open heart surgery

Interventions

non-AKI group :Urine and plasma levels of miRNA21 were assessed on 1st day following surgery

non-progression AKI group:Urine and plasma levels of miRNA21 were assessed after AKI

progression AKI group:Urine andplasma levels of miRNA-21 were assessed after AKI

Eligibility

Sex/Gender

All

Age

19 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing opn heart surgery between Jan. 2015 and Jun. 2015; 2. Age more than 18 years; 3. At least one preoperative risk factor for postoperative acute kidney injury.

Exclusion criteria

Exclusion criteria: 1. patients rejecting or doing not write informed consent; 2. end-stage renal disease; 3. concomitant tumor; 4. concomitant infectious disease; 5. preoperative kidney injury in advanced stage.

Design outcomes

Primary

Measure	Time frame
Urine and plasma levels of miRNA21;plasma creatinine;	—

Countries

China

Contacts

Public ContactDing WenJun

dwj12191@163.com+86 13564980808

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026