Population pharmacokinetics of dexmedetomidine in children

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-OPC-14005659

Enrollment

Unknown

Registered

2014-09-03

Start date

2014-12-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Disease

Interventions

MD:1.5ug/kg Dexmedetomidine infusion in 10min

HD:2.0ug/kg Dexmedetomidine infusion in 10min

LD:1ug/kg Dexmedetomidine infusion in 10min

Eligibility

Sex/Gender

All

Age

1 Years to 10 Years

Inclusion criteria

Inclusion criteria: 39 children undergoing selected operation under general anesthsia, ASA I-II, aged 1-10years.

Exclusion criteria

Exclusion criteria: Exclusion criteria included a history of serious head trauma, chronic use of any medication, previous treatment with alpha-2 agonists or antagonist within the past 30 days, or use of enzyme inducing medication, (eg. anticonvulsants) within 24 h of surgery.

Design outcomes

Primary

Measure	Time frame
blood concentration of dexmedetomidine;	—

Countries

China

Contacts

Public ContactHuacheng Liu

huachengliu@163.com+86 13957770577

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 10, 2026