Closing the Loop for Adult Subjects with T1DM Using Learning-Type Model Predictive Control

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OPC-14005355

Enrollment

Unknown

Registered

2014-10-14

Start date

2012-06-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 1 diabetes mellitus

Interventions

Case series:learning-type model prediction

Eligibility

Sex/Gender

All

Age

16 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) 16~60 years of age; (2) T1DM for at least 1 year; (3) Free of major micro- and macrovascular complications of diabetes; (4) Wear insulin pump more than half a year; (5) Subjects participating in exercise studies will undergo cardiac stress testing prior to be involved in any exercise sections of the protocol.

Exclusion criteria

Exclusion criteria: (1) Unwilling to perform repeated glucose checks or take insulin as instructed; (2) Unstable blood glucose, large fluctuations in blood glucose throughout the day; (3) Ketone symptoms poisoning, infection, and other stress state; (4) Immune system disease; (5) Severe liver or kidney disease; (6) Severe heart failure or hear failure symptoms; (7) Hematophobia blood; (8) Poor blood clotting.

Design outcomes

Primary

Measure	Time frame
average BG and deviations from normoglycemia;	—

Secondary

Measure	Time frame
inter-quartile range (IQR);Control Variability Grid Analysis (CVGA);	—

Contacts

Public ContactWenying Yang

ywying_1010@163.com+86 13601233217

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026