connective tissue diseases
Conditions
Interventions
HU-MSCs treatment group:HU-MSCs intravenous infusion
Sponsors
Southwest Hospital, Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patient has signed informed consent for mesenchymal stem cell treatment and is willing to return for follow-up visits; 2. Age range 18 to 70 years,gender unlimited; 3. Patients with connective tissue diseases, such as rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis/polymyositis, systemic sclerosis, primary sj?gren syndrome or systemic vasculitis; 4. patients were inadequate response for the conventional therapy.
Exclusion criteria
Exclusion criteria: Patients were excluded from this study for any of the following reasons: age 70 years; pregnant or lactating, if applicable; known to be allergic to any test medication; serious concomitant cardiac, cerebral, hepatic, renal, hematological or endocrine disorders; impaired consciousness or psychiatric disorders; complicating severely active infection; HIV carrier; drug addiction; participation in any other clinical studies within the previous three months; or other reasons at the discretion of investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ESR;CRP;T cell subgroup count;IgG IgM IgA;DAS28 score; | — |
Countries
China
Contacts
Public ContactYong Wang
Outcome results
None listed