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A prospective, randomized, controlled clinical study: Could atosiban improve clinical pregnancy rates in patients with two implantation failure in fresh IVF cycles?

A prospective, randomized, controlled clinical study: Could atosiban improve clinical pregnancy rates in patients with two implantation failure in fresh IVF cycles?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-OOR-16008505
Enrollment
Unknown
Registered
2016-05-20
Start date
2016-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

trial group:atosiban and luteal support medicine
control group:luteal support medicine

Sponsors

Reproductive & Genetic Hospital of CITIC-XIANGYA
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 37 Years

Inclusion criteria

Inclusion criteria: 1. met the IVF selection criteria; 2. controlled ovarian stimulation IVF treatment; 3. regular menstrual cycle; 4. aged <=37 years; 5. BMI<=28kg/m2; 6. Secondary embryo-transfer failure; 7. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Uterine malformations ,intrauterine adhesions; 2. Uterine fibroids,multiple uterine fibroids,Intramural uterine fibroids>3cm,Submucosal fibroids; 3. endometrial thickness on the daay of embryo transfer<8mm; 4. Hydrosalpinx; 5. only one quality embryo; 6. transplantation difficulties; 7. use donor eggs; 8. PGD/PGS; 9. Cancel transplant because of OHSS or unfertilized; 10. Blastocyst transfer; 11. Natural cycles or IVM; 12. Participate in other clinical trials.

Design outcomes

Primary

MeasureTime frame
clinical pregnancy rate;

Secondary

MeasureTime frame
uterine contractions rate;embryo implantation rate;early abortion rate;multiple pregnancy rate;ectopic pregnancy rate;

Countries

China

Contacts

Public ContactGong Fei

Reproductive & Genetic Hospital of CITIC-XIANGYA

lj_0305@126.com+86 0731-82355100

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026