donor kidney transplant
Conditions
Interventions
1:Caspofungin
2:None
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. receiving kidney transplantation for the first time; 2. deceased donor kidney transplantion or relative living donor kidney transplantion; 3. no fungal infections in donors and recipients before surgery; 4. both donors or recipients had no history of use of antifungal drugs prior to surgery; 5. recipients receiving a triple immunosuppressive regimen including tacrolimus, mycophenolate mofetil and prednisone after surgery; 6. participants (or their family members) consented to voluntarily participate by signing the appropriate informed consent paperwork.
Exclusion criteria
Exclusion criteria: (1) Donors or recipients with suspected, to be diagnosed or diagnosed invasive fungal infections; (2) donors or recipients with history of use of antifungal drugs; (3) recipients with abnormal liver function before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fungal infections, and high risk factors for fungal infection after kidney transplantation;Serum creatinine levels and drug trough concentration in each group; | — |
Countries
China
Contacts
Public ContactWenjun Shang
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed