Cerebral artery occlusion
Conditions
Interventions
Interventional recanalization group:Interventional recanalization
Hybrid surgery group:Hybrid surgery
Sponsors
Henan Provincial People' Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age 30-90 years old; 2. Detection of non-acute large cerebral artery occlusion (TICI grade 0); 3. Cerebral artery occlusion for more than 24 hours (imaging confirmed, or inferred from the responsibility ischemic events); 4. Ischemic responsibility events are associated with occlusive cerebral artery (including Stroke, TIA); 5. mRS scale score =4; 6. Patients are willing to go to the institution or the physician of this study for the regular follow-up; 7. Patients and their families can conduct telephone follow-up; 8. Patients could understand the meaning and purpose of this study and sign the consent form.
Exclusion criteria
Exclusion criteria: 1. Stroke of the lesion with a maximum diameter of = 5cm or transverse to the midbrain or pons 3/4; 2. Any hemorrhagic stroke within 14 days; 3. Simultaneous detection of more than two large vessels of non-acute occlusion, and can not determine the responsibility of blood vessels; 4. Occlusion of blood vessels near the heart or distal end of any residual vascular diameter = 1.5mm; 5. Occlusion caused by the following non-atherosclerotic diseases such as arterial dissection, Takayasu's disease, moyamoya; herpes simplex virus, herpes zoster virus or other virus-induced vascular disease; neurosyphilis; leptospira Vasculitis; any type of intracranial infection; radiation-induced vascular occlusion; fibromuscular dysplasia; sickle red blood cell anemia; 6. Within 30 days of any intracranial hemorrhage (including subarachnoid hemorrhage, subdural or epidural hemorrhage); 7. Have had the primary intracranial or ventricular hemorrhage 8. Within 30 days before or within 90 days of major surgery (including femoral artery, aorta or carotid artery surgery); 9. Activated gastrointestinal ulcers, 30 days of systemic bleeding, active bloody diarrhea, platelet count 1.5, coagulation factor abnormalities lead to increased risk of bleeding; 10. Severe liver damage (ALT or AST> normal upper limit 3 times, cirrhosis), creatinine> 3.0 (unless the patient is dialysis); combined heart, respiratory failure; 11. Clearly allergic or contraindicated to aspirin, clopidogrel, heparin, stent component nickel-titanium alloy and local anesthetic or general anesthetic; 12. On the contrast agent has a history of fatal allergies; if allergic but not fatal, can be preoperative by the specialist carefully assessed after the effective prevention; 13. Life expectancy of no more than 3 years; and combined intracranial or extracranial malignant tumors; Combined with malignant tumors; with the heart, liver, kidney, lung and other vital organs or functional failure; 14. Other studies that have been included may be in conflict with current research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stroke; | — |
Countries
China
Contacts
Public ContactTianxiao Li
Henan Provincial People's Hospital
Outcome results
None listed