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The effect of propofol and dexmedetomidine sedation on auditory evoked potentials and EEG coherence:from wakefulness to conscious sedation, deep sedation and recovery

The effect of propofol and dexmedetomidine sedation on auditory evoked potentials and EEG coherence:from wakefulness to conscious sedation, deep sedation and recovery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OON-16008369
Enrollment
Unknown
Registered
2016-04-26
Start date
2015-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

No target disease

Interventions

Dex:reveive Dex sedation
Pro:receive propofol sedation

Sponsors

Beijing Tongren Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Twenty healthy male subjects(ASA physical status I, right-handed, non-smoking, normal-weight), aged 25–30 years, will be enrolled in this study. All subjects should receive a detailed pre-study examination including an interview, physical status assessment, laboratory testing and a 12-lead ECG. Subjects are not allowed to use alcohol or any medication 48 hours before the study and all fasted at least 8 hours.

Exclusion criteria

Exclusion criteria: Male subjects who have cardiovascular problems,mental disease or severe bradycardia will be exclude from this study.

Design outcomes

Primary

MeasureTime frame
the amplitude and latency of AEFP;BIS value;counting ability;

Countries

China

Contacts

Public ContactTianzuo Li

Beijing Shijitan Hospital

trmzltz@126.com+86 13911072068

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026