Meibomian GlandDysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: IPL group: 1) meibomian glanddysfunction grade 2-3; 2) Fitzpatrick sun-reactive skin typing I-IV; 3) patients have wishes to improve orbital skin problem (including pigmented or vascular dermopathy andacne) andhave no history of intense pulsed light treatment. Control group: 1) being matched in age with IPL group; 2) meibomian glanddysfunction grade 2-3.
Exclusion criteria
Exclusion criteria: 1) acute episodes of ocular surface or facial skin diseases; 2) history of sun exposure or allergy disease within one month; 3) any topical or systemic diseases which are possible to affect results (facial skin cancer, recurrent herpes simplex, graft-versus-host disease, systemic lupus erythematosus andetc.); 4) surgical history of treatment andocular areas, andmedical history of any other treatment which may affect results andthe intense pulsed light treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Break-up Time;Ocular surface disease index (OSDI);MGD grading;meibomian glanddropout;meibomian glandmorphology; | — |
Secondary
| Measure | Time frame |
|---|---|
| Schirmer I test;cornea andconjunctiva stainning;anterior segment evaluation; | — |
Countries
China