Lumbar Degenerative Diseases
Conditions
Interventions
A:Posterior Dynamic Stabilization
B:Internal Fixation and Fusion
Sponsors
The first Affiliated Hospital of Third Military Medical University, PLA
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Signed informed consent; 2. Age between 30 and 75 years inclusive; 3. Radiographic evidence of multi-level lumbar disc degeneration disease; 4. Scheduled for 2- or 3-level lumbar discectomy at levels from L1 to S1 with or without dynamic stabilization or fusion; 5. Preoperative ODI = 30 6. Clinical symptoms consistent with diagnosis of lumbar DDD: (1)Radicular back or lower extremity pain and/or (2)Decreased muscular strength and/or (3)Abnormal sensation. 7. Failed to gain adequate symptom relief from at least one month of adequate non-operative treatment.
Exclusion criteria
Exclusion criteria: 1. Cauda equina syndrome; 2. Patients with other lumbar conditions that will, in the opinion of the investigator, interfere with clinical outcomes (e.g. spinal structural deformities, spinal fractures, ankylosing spondylitis, spinal tuberculosis, spinal infection, spinal tumors, symptomatic cervical spinal disease); 3. Osteoporosis defined as T-score = -3.5. BMD will be measured by DEXA performed on lumbar spine; 4. Systemic infection such as AIDS and active hepatitis; 5. Recent history (less than 3 years) of chemical substance dependency or significant psychosocial disturbance, which may impact the outcome or study participation; 6. Participation in a clinical trial of investigational drug or device within the past 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ROM of Lumbar; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oswestry Disability Index (ODI); | — |
Countries
China
Contacts
Public ContactZhou Qiang
Outcome results
None listed