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Study on the optimization of the individualized regimen of tacrolimus in the early stage of liver transplantation in children

Study on the optimization of the individualized regimen of tacrolimus in the early stage of liver transplantation in children

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-17014191
Enrollment
Unknown
Registered
2017-12-28
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver transplantation in children

Interventions

Liver transplantation group:Liver transplantation

Sponsors

Tianjin First Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 14 Years

Inclusion criteria

Inclusion criteria: 1. The first liver transplantation was performed in the center for the first time from 2017.01.01 to 2018.12.31, and no other organ transplantation was accepted at the same time; 2. All the recipients were 0-14 children with liver transplantation; 3. After surgery with tacrolimus as the basis of immunosuppressive agents, can be combined with mycophenolate mofetil and methylprednisolone.

Exclusion criteria

Exclusion criteria: 1. Patients were given tacrolimus for less than 3 months or replaced with other immunosuppressive agents; 2. Two liver transplants or postoperatively accepted renal transplantation; 3. Taking the effect of tacrolimus blood concentration drugs such as phenytoin sodium, rifampicin, cimetidine, fluconazole; 4. The follow-up time was less than 3 months.

Design outcomes

Primary

MeasureTime frame
FK506 concentration;

Countries

China

Contacts

Public ContactZhang Yi

Tianjin First Central Hospital

wing_zh1821@sina.com+86 13512990209

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026