Brain Arteriovenous Malformations
Conditions
Interventions
Transarterial embolization, microsurgical, stereotactic radiosurgery grope:Interventional embolization, resection, radiosurgery
Transvenous interventional embolization group:Interventional embolization
Sponsors
Henan Provincial People' Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 6-60 years old; 2. Nidus size = 6cm: CTA, MRA, and MRI were the most common diagnostic methods for Nidus, but the size of BAVM was determined by DSA; 3. Preoperative nidus has ruptured; arterial feeds is slender, tortuous and narrow; a main draining vein, which collects 80% blood of the nidus ,and the structure can be identified to make microcatheter enter the nidus through the vein; 4. Patients can tolerate hypotension; 5. Patients are willing to attend the study and the ability to regularly follow-up; 6. Patients can understand the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients suffered from any of the following diseases: multiple BAVM, venous malformation,cavernous hemangioma, hereditary hemorrhagic telangiectasia,moyamoya ndisease; 2. Although the medical treatment,still can not tolerate general anesthesia; 3. Because of Vascular severe tortuosity or anatomical factors , arterial sheath, the guiding catheter is difficult to internal carotid artery or vertebral artery; 4. Thrombosis occurs in the vessel wall near the lesion or at the lesion site; 5. Severe allergy history of contrast agents or medical glue; 6. Active bleeding or coagulopathy, activated gastrointestinal ulcers, 30 days of systemic bleeding, platelet count 1.5, the bleeding time more than the upper limit of normal 1min or heparin associated thrombocytopenia more, severe hypertension hemorrhage risk not control (systolic pressure >180mmHg or diastolic pressure >115mmHg), severe liver injury: AST and ALT more than the normal 3 times, Cirrhosis and severe injury of renal function (creatinine >265.2 mol/L); 7. Within 30 days before or within 90 days of major surgery (including femoral artery, aorta or carotid artery surgery); 8. Failure to understand the contents of cooperative trials and to sign informed consents; 9. Severe dementia or mental disorders cannot be followed up; 10. Female patients during pregnancy; 11. Combined with other lesions, the patient expected survival for <3 years; 12. Other studies that have been included may be in conflict with current research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stroke;Size of nidus; | — |
Countries
China
Contacts
Public ContactWeixing Bai
Henan Provincial People's Hospital
Outcome results
None listed