Acromegaly
Conditions
Interventions
Surgery Group:Surgery such as Transnasal butterfly surgery
Drug Group:Drug treatment includes somatostatin analogues (SSA), dopamine receptor agonists and GH receptor antagonists
Radiotherapy Group:Conventional radiotherapy methods include radiotherapy, linear accelerator X knife, gamma knife
Sponsors
Huiwen Tan, Zhiyong Chen
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: The patient population that will be observed in the study must fulfill all of the following criteria: 1. Be able and willing to sign the informed consent form (ICF); 2. Male, female, aged 18-75 years old (including 18 years old and 75 years old); 3. Compliance with acromegaly diagnostic criteria: (1) At least one laboratory or medical record shows that the patient is random GH = 2.5 ug/L; (2) At least one checklist or medical record shows radiographic evidence that the patient has a pituitary tumor.
Exclusion criteria
Exclusion criteria: Patients meeting any of following exclusion criteria will not be eligible: 1. Ectopic secretion of GH or pituitary cancer; 2. The patient is diagnosed with other complicated malignancies, or has previously been diagnosed with another malignancy, and there is currently evidence of lesion residue; 3. Have a diagnosis of other severe acute or chronic medical or psychiatric conditions that may increase the risk associated with study participation or may interfere with the interpretation of the study results and, in the judgement of the Investigator, would make the patient inappropriate for enrollment in this study; 4. Those patient who, in the judgement of the Investigator, to be inappropriate for enrollment in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cause of death; | — |
Secondary
| Measure | Time frame |
|---|---|
| GH;IGF-1;Acromegaly symptoms;Questionnaire (ACROQoL?EQ-5D-3L);Radiographic image; | — |
Contacts
Public ContactShengrong Xie
Nanjing Yuhua GinkgoLeaf Rare Disease Family Care Centre
Outcome results
None listed