Advanced digestive system tumors
Conditions
Sponsors
81th Hospital of PLA, Dongfang Hospital Affiliated to Shanghai Tongji University
Eligibility
Sex/Gender
All
Age
8 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years old, male or female; 2. Pathological examination of the diagnosis of advanced digestive system malignancy, the need for anti-cancer drug chemotherapy; 3. able to take surgical resection or biopsy to obtain fresh tumor tissue; 4. Objective objective tumor in line with RECIST 1.1, CT / MRI can be used to evaluate efficacy; 5. ECOG score 0 ~ 2, the expected survival time to be = 3 months; 6. For previous postoperative subjects, previous anti-cancer drug therapy (chemotherapy and / or targeted therapy) failure from the group of study time to be = 4 weeks, and adverse reactions have been basically restored; 7. Participants volunteered to sign informed consent, good compliance, active treatment and follow-up.
Exclusion criteria
Exclusion criteria: 1. Participate in other drug clinical studies at the same time; 2. liver, kidney function and bone marrow hematopoietic function does not meet the requirements of chemotherapy; 3. Do not want to use the researchers after the failure of the previous treatment with the results of the recommended anti-cancer drugs or programs for follow-up chemotherapy; 4. suffering from severe uncontrolled acute infection or major organ disease; 5. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ORR;DCR;Serum tumor markers; | — |
Countries
China
Contacts
Public ContactQin shukui
81th Hospital of PLA
Outcome results
None listed