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Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. search in the 2012-2017 medical record of Guangzhou Women and Chlidren's Medical Center; 2. exposed to =2 general anesthesia before 3 years old; 3. the anesthesia time is longer than 1h; 4. finish Informed consent.
Exclusion criteria
Exclusion criteria: 1. serious complication at peri-operative period; 2. exist central nervous system disease or malformation; 3. have been diagnosed as cognitive development delay before the first surgery; 4. neurosurgery and malignant tumor patient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wechsler intelligence score; | — |
Secondary
| Measure | Time frame |
|---|---|
| gesell score;M-chat score;ADHD;DEXA;ASD;microelement; | — |
Countries
China
Contacts
Guangzhou Women and Chlidren's Medical Center?