infertility
Conditions
Interventions
1:weight loss by lifestyle modification
2:none
Sponsors
Reproduction and Genetics Hospital of the First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
Female
Age
18 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1. PCOS diagnosed by Rotterdam criteria; 2. Body mass Index =25kg/m2; 3. Aged 18-39 years; 4. With previous good health, no serious systemic disease history; 5. Voluntary participation in clinical trials; 6. Sperm concentration>10×10^6/ml.
Exclusion criteria
Exclusion criteria: 1. Endometriosis (cystic, glandular myopathy/tumor); 2. impaired ovarian function; 3. Congenital uterine/genital tract malformation female; 4. Congenital chromosomal abnormalities in women (such as Turner syndrome); 5. Previous uterine, fallopian tube, ovary surgery history; 6. hypertension and coronary heart disease, diabetes family history; 7. History of thyroid and adrenal diseases; 8. No other serious illness resulted; 9. Other clinical trials that may have affected the results of the trial in one months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate;BMI;ovulation rate;live birth rate;miscarriage rate;body weight; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting insulin;triglycerides;total testosterone;total cholesterol;high-density lipoprotein cholesterol;low-density lipoprotein cholesterol;blood pressure;antral follicle counts; | — |
Countries
China
Contacts
Public ContactYihong Guo
Reproduction and Genetics Hospital of the First Affiliated Hospital of Zhengzhou University
Outcome results
None listed