cervical cancer
Conditions
Interventions
cytology is HSIL/ASC-H:cervical conization
Punch biopsy is HSIL:cervical conization
Patient with any one of following conditions below: HPV16/18 positive, cytology finds ASCUS with HPV positive, or AGC with HPV positive, or LSIL(HPV test is not necessary), colposcopy finds HSIL with
Sponsors
The Obstetrics and Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Aged 25-65 years old; 2) The result of cytology is HSIL/ASC-H(HPV test is not necessary), no matter what the result of colposcopy and histologic biopsy are. A total of 1000 cases are needed; 3) Punch biopsy is HSIL, no matter what the result of colposcopy and cytology are. A total of 1000 cases are needed; 4) Any one of the conditions below: HPV16/18 is positive,cytology is ASCUS with HPV positive, cytology is AGC with HPV positive, cytology is LSIL(HPV test is not necessary), the result of colposcopy is HSIL with biopsy LSIL. A total of 1000 cases are needed; 5) Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patient was treated by cervical conization; 2) Acute inflammation of the pelvic cavity and lower reproductive tract; 3) Patients in pregnancy, unless highly suspected cervical infiltration cancer; 4) Patients with severe underlying diseases, which may result in the inability to therapy safely. These diseases include but not limited to persistent or active infection, symptomatic congestive heart failure, unstable angina,arrhythmia, mental disorder, social situations (which may limit the compliance of patients to the research requirements).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cytology;High risk HPV test;colposcope; | — |
Countries
China
Contacts
Public ContactLong Sui
The Obstetrics and Gynecology Hospital of Fudan University
Outcome results
None listed