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The study on population pharmacokinetics of oxcarbazepine bassed on genetic testing

The study on population pharmacokinetics of oxcarbazepine bassed on genetic testing

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-17012141
Enrollment
Unknown
Registered
2017-07-26
Start date
2017-08-01
Completion date
Unknown
Last updated
2017-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy

Interventions

Case series:oxcarbazepine

Sponsors

The Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. inpatient or outpatient in The second affiliated hospital,school of medicine,Zhejiang university,who are diagnosed with epilepsy and are Chinese adult han patients; 2. aged 18-90 years old; 3. received OXC as monopharmacy or in combination with either the antiepileptic drugs,use a dose to last more than 2 weeks for stable plasma concentration; 4. To fully understand the purpose of this study and to understand possible adverse reactions, volunteer to participate in the experiment and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. There are serious adverse reactions to OXC; 2. Have any progressive or degenerative systemic disease or central nervous system disease or brain tumor and other organic brain diseases; 3. Acute epileptic seizures, Such as epilepsy after brain surgery, acute epilepsy induced by viral encephalitis, acute epilepsy after trauma, etc.

Design outcomes

Primary

MeasureTime frame
Genetic testing;Blood drug concentration monitoring;Liver and kidney function;Routine blood;

Countries

China

Contacts

Public ContactHaibin Dai

The Second Affiliated Hospital, School of Medicine, Zhejiang University

haibindai@163.com+86 13600527604

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026