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The effect and mechanism of Propofol on ventricular arrhythmias

The affect and mechanism of Propofol on ventricular arrhythmias

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-OOC-17011821
Enrollment
Unknown
Registered
2017-06-30
Start date
2017-11-06
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature ventricular contraction

Interventions

Intervention group:Low dose intravenous injection of propofol (50mg)

Sponsors

Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. All the patients who will be scheduled for ablation for ventricular arrhythmias and agree to use propofol as preoperative anesthetic drug; 2. Ventricular arrhythmias burden greater than 20%; 3. No contraindication for EPS and ablation; 4. Aged from 18 to 80 years old.

Exclusion criteria

Exclusion criteria: 1. Patients with severe chronic lung disease, anesthesia risk; 2. Sevious congenital heart diseases, post myocardiac infarction, hypertrophic obstructive cardiamytopathy, dialated cardiacmyopathy; 3. With pregnancy; 4. With allergic history for Propofol; 5. Blood pressure less than 90/60mmHg.

Design outcomes

Primary

MeasureTime frame
Responce to propofol (Does premature ventricular contractions/tachycardia disappear after medication or does the patient experience circulatory or respiratory system disorders);

Countries

China

Contacts

Public ContactDong Huang

Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University

huangdong1004@126.com+86 189 3017 3998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026