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Association of long time propofol or sevoflurance anesthesia in infancy with the neurocognitive performance in later childhood

Association of long time propofol or sevoflurance anesthesia in infancy with the neurocognitive performance in later childhood

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-17011712
Enrollment
Unknown
Registered
2017-06-20
Start date
2018-01-01
Completion date
Unknown
Last updated
2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

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Interventions

sevoflurance group:sevoflurance anesthesia
propofol group:propofol anesthesia
control group:no intervention

Sponsors

Guangzhou Women and Chlidren's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 2 Years

Inclusion criteria

Inclusion criteria: 1. aged 1-4 months, ASA I-II; 2. abdomenal surgery; 3. predict anesthesia time 2-6h; 4. live in Guangzhou more than 3 years; 5. finish Informed consent.

Exclusion criteria

Exclusion criteria: 1. gestational age <37 weeks; 2. mother exposure to general anesthesia at pregnancy; 3. with congenital malformation which may be harmful to neurocognitive development; 4. with neurocognitive disease before the surgery; 5. preoperative DST test shows developmental retradation; 6. predict lifetime is less than 5 years such as cancer or serious heart disease; 7. contraindication to caudal anesthesia or general anesthesia; 8. have been long time exposure to general aneshtesia before this surgery.

Design outcomes

Primary

MeasureTime frame
Attributional Style Questionnaire (ASQ) score;Gesell score;—

Countries

China

Contacts

Public ContactXingrong Song

Guangzhou Women and Chlidren's Medical Center

songxr1966@sohu.com+86 13922416303

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026