intracerebral aneurysm
Conditions
Interventions
Sponsors
Beijing Neurosurgical Institute
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Ophthalmic segment aneurysms diagnosed by MRA, CTA or DSA. The aneurysms include both ruptured (the interval between treatment and SAH should be more than 3 weeks) and unruptured, aneurysms treated for the first time or recurrent aneurysms. The shape of the aneurysms can be saccular, fusiform, blood-blister-like, and pseudo-aneurysm; 2. The patient ages between 18 and 75 years old; 3. Target vessel diameter ranges from 3.5-4.5mm; 4. The general state of the patients are suitable for treatment with intracranial deployment of a Willis covered stent through intravascular route; 5. Subject has provided written informed consent and is willing to participate the trial and comply with the required follow up.
Exclusion criteria
Exclusion criteria: 1) The target aneurysm is adjacent to important branches from the internal carotid artery like the anterior choroidal artery, the posterior communicating artery and ophthalmic artery. Whats more, the branch has no sufficient blood supply from other collaterals as confirmed by clinical imaging; 2) There is no appropriate endovascular route to access the aneurysms through a tortuous vessel; 3) Acutely ruptured aneurysms (SAH within 3 weeks) and patients with extra-ventricular drainage; 4) Patients with severe systematic disease or the general state is too weak for endovascular treatment. Those conditions including bleeding disorders, dysfunction of the heart, liver and renal. Patients with systematic infection and pregnant woman should be excluded; 5) The life expectancy of the patient is less than one year; 6) The patients has known contradictions to heparin, aspirin, clopidogrel, general anesthesia, fluoroscopic agent and X-ray; 7) Unstable neurological state and mental deficits, unable to comply with trial and to report adverse effect of the treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| complete occlusion rate of aneurysm; | — |
Secondary
| Measure | Time frame |
|---|---|
| procedural safety;stenosis degree of parent artery;clinical prognosis;Incidence of device-related adverse events;cerebrovascular event ratte; | — |
Countries
China
Contacts
Public ContactChuhan Jiang
Beijing Neurosurgical Institute d Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed