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Central Response Mechanism for acupuncture and acupoint by functional magnetic resonance image in brain

Investigation on Functional Connectivity of Default Mode Network Based on Resting State fMRI in Brain after Needle Acupoints on Xinbao Meridian in Subjects with Mild Depression and Healthy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-17011452
Enrollment
Unknown
Registered
2017-04-11
Start date
2017-06-01
Completion date
Unknown
Last updated
2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild depression

Interventions

Healthy AND Mild depression:Acupuncture

Sponsors

The Henan University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: (1) Mild depression subjects Mild depression subjects which showed symptoms consistent with the Chinese Classification and Diagnostic Criteria of Mental Disorders third edition diagnostic criteria of mild depression (aged 18-30 years, disease courage: 2-12months, education: 12-16 years). The Hamilton Depression Scale scores of these subjects were greater than or equal to 17 and lesser or equal to 17. All subjects are no scar left in left forearm and no metal in body (such as heart stent); (2) Healthy subjects Healthy subjects (aged 18-30 years, education: 12-16 years) which was right handedness and had no history of psychiatric or neurological disease and had regular diets and normal sleep habits and did not smoke, drink wine, tea, coffee or alcohol at the time of the study. All subjects are no metal in body (such as heart stent).

Exclusion criteria

Exclusion criteria: Exclusion criteria (1) Mild depression subjects Pregnant or lactating women, patients with severe respiratory, circulatory, neurological, metabolic and endocrine disorders, abusers of alcohol and drug dependence, suicidal tendency by evaluated, patients with bipolar depression, post schizophrenia depression and other depressive disorders, Subjects which were physical pain symptoms (including dysmenorrhea) had not received any acupuncture treatment or oral medication history within 1 week before fMRI scan.Subjects were identified as a non acupuncture response or an excessive acupuncture response by the same professional acupuncturist across the acupuncture response trail before test beginning (1 months ago). Subjects are participating in other clinical trials or are not suitable for clinical trials with other causes by researchers; (2) Healthy subjects Subjects which were physical pain symptoms (including dysmenorrhea) had not received any acupuncture treatment or oral medication history within 1 week before fMRI scan. Subjects were identified as a non acupuncture response or an excessive acupuncture response by the same professional acupuncturist across the acupuncture response trail before test beginning (1 months ago). Subjects are participating in other clinical trials or are not suitable for clinical trials with other causes by researchers.

Design outcomes

Primary

MeasureTime frame
Functional connection of the Hippocampus based seeds;Functional cnnection of the Amygdala based seeds;Functional connection of the Buckle back based seeds;fractional amplitude of low frequency fluctuation;

Countries

China

Contacts

Public ContactHan Hongyan

The Henan University of Traditional Chinese Medicine

hhy13103617028@126.com+86 13838364722

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026