Alterations of glucose tolerance and pancreatic islets function of diabetic patients after sleeve gastrectomy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OOC-17011074

Enrollment

Unknown

Registered

2017-04-06

Start date

2017-12-01

Completion date

Unknown

Last updated

2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

sleeve gastrectomy group:None

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.T2DM duration less than 10 years with endocrine function of pancreatic islets remained; 2.BMI 27.5 to 40; 3.Aged between 18 and 65 years old.

Exclusion criteria

Exclusion criteria: 1.Type 1 diabetes mellitus; 2.No function of B cells of pancreatic islets; 3.Gestational diabetes mellitus; 4.Drug or alcohol abuse and uncontrollable mental disorder; 5.Patients with poor compliance in alteration of diets and life style; 6.Intolerance of surgery or anesthesia because of poor body condition.

Design outcomes

Secondary

Measure	Time frame
waistline;Serum lipid;	—

Primary

Measure	Time frame
Oral glucose tolerance test;Intravenous glucose tolerance test;PET-CT;GLP-1;GIP;Ghrelin;Fasting plasma glucose;HbA1c;BMI;	—

Countries

China

Contacts

Public ContactLiu Shaozhuang

Qilu Hospital of Shandong University

16416448@qq.com+86 18560085165

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026