Inflammatory Bowel Disease
Conditions
Interventions
Two cohorts:azathioprine treatment
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
16 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of inflammatory bowel disease (clinical diagnosis and / or pathological diagnosis); 2. Aged from 16 to 70 years old, male or female; 3. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe heart and (or) liver and kidney dysfunction; 2. Mucosal biopsy implied cancer or lymphoma; 3. Active tuberculosis; 4. Active viral hepatitis: significant elevated transaminase (greater than 2 times the upper limit of normal), and / or hepatitis B HBeAg and viral replication DNA> 10^5copies / ml or small positive virus replication greater than 10^4copies / ml; 5.Complication with bacterial or viral infection has not been effectively controlled; 6. Acute abdomen, or other indications for surgery (complicated with fistula, fibrous stenosis caused by intestinal obstruction, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NUDT15 gene polymorphism;TPMT gene polymorphism; | — |
Countries
China
Contacts
Public ContactWang Honghui
Xiangya Hospital, Central South University
Outcome results
None listed