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Oral Phosphate Supplements Play an Important Role in Improving the Bone Mineral Density of Hypophosphatemic Osteomalacia Patients

Effect of Phosphate on hypophosphatemia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-16010095
Enrollment
Unknown
Registered
2016-12-07
Start date
2006-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypophosphatemic Osteomalacia

Interventions

A1:received phosphate solution doses at a frequency dependent upon measured serum phosphorus levels
A2:received phosphate solution doses only every three to four days
A3:received no phosphate solution
A:Hypophosphatemic Osteomalacia

Sponsors

The Second Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: At three affiliated hospitals of Central South University (Xiang-Ya Hospital, the Second Xiang-Ya Hospital, the third Xiang-Ya Hospital) from January 1, 2006 to September 1, 2013. 21 patients (13 males and 8 females) diagnosed with hypophosphatemic osteomalacia were selected as the case group. 105 age, sex, height, and weight matched participants with normal blood biochemical and BMD measurements and no systemic disease were selected as the control group.

Exclusion criteria

Exclusion criteria: Patients with underlying phosphorus imbalance stemming from chronic disease and/or tumors were excluded

Design outcomes

Primary

MeasureTime frame
BMD;BA;BMC;serum P;

Secondary

MeasureTime frame
serum Ca;serum ALP;

Countries

China

Contacts

Public ContactHou-De Zhou

The Second Xiangya Hospital, Central South University

houdezhou@csu.edu.cn+86 0731 85292150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026