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Study of CTCs detection in neoadjuvant chemotherapy for stage III esophageal cancer

Circulating Tumor Cell Detection Technology to Guide China's Common Digestive System Malignant Tumor Surgical Precise Treatment

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-16009940
Enrollment
Unknown
Registered
2016-11-20
Start date
2016-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

Surgery group / neoadjuvant chemotherapy + surgery group:neoadjuvant chemotherapy

Sponsors

Second Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Preoperative endoscopic biopsy pathology confirmed esophageal squamous cell carcinoma, endoscopy, and endoscopic ultrasound comprehensive assessment of tumor location and depth of invasion, chest and abdomen enhanced by CT comprehensive assessment of tumor invasion and the number of suspected lymph node metastasis, if necessary (T1-2N2, T3N1-2, T4aN0-2), and some patients with stage II (such as stage III, stage III, and stage III) were treated with endoscopic ultrasonography or B-mode ultrasonography. T1-2N1 or other patients with stage II will also be enrolled).

Exclusion criteria

Exclusion criteria: Liver, lung, brain, kidney and other organ complications; esophageal cancer associated with perforation to the lungs to form a lung abscess, thoracic tumor, a history of malignancy; TNM stage IIIc-IV (T4b or N3 or M1); The lower esophageal cancer cervical lymph node metastasis or cervical esophageal cancer, celiac artery lymph node metastasis.

Design outcomes

Primary

MeasureTime frame
Number of circulating tumor cells;

Countries

China

Contacts

Public ContactWei-di Zhang

School of Medicine and Life Science, University of Jinan, Shandong Academy of Medical Science, Shandong cancer hospital affiliated to Shandong University, Shandong Academy of Medical Science

spp128@126.com+86 18663776711

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026