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Research on the stress induced bone formation mechanism of Integrative Medicine hallux valgus finite element model

Research on the stress induced bone formation mechanism of Integrative Medicine hallux valgus finite element model

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OOC-16008821
Enrollment
Unknown
Registered
2016-07-11
Start date
2016-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hallux valgus

Interventions

A:Non stress stimulation
B:Given 15min / d, urging stress stimulation frequency 30 times / min.
C:Given 30min / d, urging frequency 30 times / min of stress stimulation
D:Given 60min / d, urging stress stimulation frequency 30 times / min.

Sponsors

Wangjing Hospital of China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Diagnostic criteria in line with hallux valgus; 2. Patients need surgery after conservative treatment systems; 3. No surgical contraindications; 4. Patients agreed to participate in the research and signed informed consent.

Exclusion criteria

Exclusion criteria: Patients neither without surgical indications nor do not meet the inclusion criteria will not be included in this study.

Design outcomes

Primary

MeasureTime frame
Fibroblast activity assay;Morphological observation;Purity and cell apoptosis;osteocalcin, ALP, calcified nodule;

Secondary

MeasureTime frame
Type 1 collagen;TGF-ß3;

Countries

China

Contacts

Public ContactJianmin Wen

Wangjing Hospital

wjm5734@263.net+86 13901115340

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026